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Sedikit saja penggunaan zat ini sudah bisa mengacaukan kadar zat kimia alami dalam otak yang disebut dopamin. Produksi dopamin secara berlebihan dapat menyebabkan rasa gembira berlebihan dan sensasi melayang-layang (large). Biasanya sensasi tersebut diikuti dengan gejala seperti di bawah ini.Če te po uporabi kokaina tišči v prsih oz. se bolečin